This comforting casserole recipe, often referred to as “Mexican Chicken Casserole,” combines Tex-Mex flavors with classic American ingredients. Popular across Southern kitchens, especially in Texas, this dish layers Doritos with seasoned chicken, creamy soups, and zesty Rotel tomatoes. It originated in mid-20th century American home cooking when canned soups became staples in quick, hearty meals. The recipe is perfect for potlucks, family dinners, or nostalgic comfort food nights. Its ease of preparation and bold flavor make it a beloved favorite passed down through generations.